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Specimen provenance complications (SPCs) result from instances of biopsy specimen transposition, extraneous/foreign cell contamination or misidentification of cells used in clinical or anatomical pathology. If left undetected, SPCs can lead to serious diagnostic mistakes and adverse patient outcomes. == Causes == According to recent reports from the American Cancer Society, an estimated 12.7 million cases of cancer were diagnosed in 2008, and that number is expected to rise to more than 20 million by 2030 due to population growth and aging alone. The problem will likely be further exacerbated by the widespread adoption of certain lifestyle factors (smoking, poor diet, physical inactivity, etc.) that increase the risk of developing the disease.〔(【引用サイトリンク】url=http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-031941.pdf )〕 The process of collecting and evaluating the biopsy specimens used to render these cancer diagnoses involves nearly 20 steps and numerous medical professionals from the time the sample is originally taken from the patient to the time it is received by pathology for analysis. With such a complex process executed at a large scale, the potential for a variety of Specimen Provenance Complications is a serious concern for both physicians and patients. While enforcement of strict protocols and procedures for the handling of samples helps to minimize error, identification issues in anatomic and clinical pathology labs still occur. The most common error is a mislabeled or unlabeled specimen. Another potential complication is the presence of a contaminant tissue fragment - commonly referred to as a floater - that does not belong to the patient being evaluated. Floaters can be introduced in the laboratory during tissue sectioning, processing or gross dissection, or potentially in a clinical setting as well when the biopsy is being performed. If one of these floaters is from a malignant specimen, a healthy patient could be falsely diagnosed as having cancer. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Specimen provenance complications」の詳細全文を読む スポンサード リンク
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